Lori Coble Car Accident:
A Southern California family once known nationwide for enduring unimaginable loss is now facing another devastating challenge, as Lori Coble has been diagnosed with an aggressive form of brain cancer. In 2007, the Mission Viejo community was shaken when Lori and her husband, Chris Coble, lost their three young children — Kyle, Emma and Katie — in a fatal crash on Interstate 5. The tragedy drew national attention, and the couple later spoke publicly about their grief and resilience, becoming a symbol of strength in the face of profound loss.
In the years that followed, the family experienced renewed hope with the birth of triplets — Ellie, Ashley and Jake — who are now high school seniors. Friends say their arrival marked a period of healing and joy after years of sorrow. That sense of stability has now been disrupted. Lori, 48, was recently taken to hospital after experiencing concerning symptoms and was diagnosed with Stage IV glioblastoma, a fast-growing and incurable brain cancer. Doctors performed emergency surgery, successfully removing around 80% of the tumour. However, part of the tumour remains behind her right eye, an area too delicate for further surgery.
Following the operation, Lori lost vision in one eye and some motor control. While doctors are hopeful that physical therapy may restore some movement, her recovery remains uncertain. Medical teams have also discovered a separate mass in her breast, unrelated to the brain cancer, which may require further surgery. Lori is expected to undergo intensive chemotherapy and radiation treatment, alongside ongoing rehabilitation and home care. During this time, Chris is balancing full-time work, caring for his wife and supporting their three teenage children.
A GoFundMe campaign has been launched to help the family manage mounting medical and living expenses. Supporters say the fundraiser is a way for the community to stand beside a family that has already endured more hardship than most. Friends and neighbours are urging people to donate and share the family’s story, saying collective support can help ease the burden as Lori begins the fight of her life.
